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This points out why a person lorazepam dose, despite its shorter serum 50 percent-life, has more prolonged peak effects than an equal diazepam dose.[99] Lorazepam is speedily conjugated at its three-hydroxy group into lorazepam glucuronide which can be then excreted while in the urine. Lorazepam glucuronide has no demonstrable CNS action in animals